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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48012f04948656a7b99d1bff1a3b7f0a55d84999c03e2d4e633d60e3f8c37a40' 
  AND token = 'ulGhfNSk3WNs7pReF7Ixm4VIpwVIjDnxVAw6h0MiglE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}