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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5848a576e77245e4e57340d15495efd872b5d073a0a27785785c703bc8dfd92' 
  AND token = 'zQNAgkaQSgjbi+zrOgKZm9RWldsniqF//t48U3lDIE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}