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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd588bd45a5974181ac05a42e83fd00a0441d5d71232553ee1fae2544f482bf1d' 
  AND token = '0NFpGpN/UOZNwo0eDnP3GMxqkxowB9W5kUUy1d/FSUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}