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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f9f5e3d183a85c1dc4e8d516cded9a4e2128815d85def2006563625440aaba3' 
  AND token = 'MzQVDjj1RZIRlxafTAwcR51smIZJjlv2LRu+DRCpLuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}