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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b38d9e51ef9b5ffb93523c29441acbba789440a81e55f45855b92405950a183' 
  AND token = 'BrPTBqY/BZ7MINeD7I9FdJox3C3zXGV/0JMbPYvYNe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}