SELECT 
  variant_id, 
  yml2_unit 
FROM 
  cscart_product_feature_variant_descriptions 
WHERE 
  variant_id IN (
    '5495', '5456', '4422', '4852', '5335', 
    '4305', '2219', '1305', '2061', '1391', 
    '1669', '1293', '2064', '2062', '2292', 
    '1315', '1397', '1969', '2099', '2063', 
    '1265', '2007', '2508', '1392', '1365', 
    '2160', '2156', '1444', '2066', '2592', 
    '1398', '1275', '1248', '2330', '1227', 
    '2467', '1242', '1402', '2386', '2065', 
    '2158', '1345', '1249', '1405'
  ) 
  AND lang_code = 'ru'

Query time 0.00088

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "30.81"
    },
    "table": {
      "table_name": "cscart_product_feature_variant_descriptions",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY"
      ],
      "key": "PRIMARY",
      "used_key_parts": [
        "variant_id",
        "lang_code"
      ],
      "key_length": "9",
      "rows_examined_per_scan": 44,
      "rows_produced_per_join": 44,
      "filtered": "100.00",
      "index_condition": "((`unicomps`.`cscart_product_feature_variant_descriptions`.`variant_id` in ('5495','5456','4422','4852','5335','4305','2219','1305','2061','1391','1669','1293','2064','2062','2292','1315','1397','1969','2099','2063','1265','2007','2508','1392','1365','2160','2156','1444','2066','2592','1398','1275','1248','2330','1227','2467','1242','1402','2386','2065','2158','1345','1249','1405')) and (`unicomps`.`cscart_product_feature_variant_descriptions`.`lang_code` = 'ru'))",
      "cost_info": {
        "read_cost": "26.41",
        "eval_cost": "4.40",
        "prefix_cost": "30.81",
        "data_read_per_join": "137K"
      },
      "used_columns": [
        "variant_id",
        "lang_code",
        "yml2_unit"
      ]
    }
  }
}

Result

variant_id yml2_unit
1227
1242
1248
1249
1265
1275
1293
1305
1315
1345
1365
1391
1392
1397
1398
1402
1405
1444
1669
1969
2007
2061
2062
2063
2064
2065
2066
2099
2156
2158
2160
2219
2292
2330
2386
2467
2508
2592
4305
4422
4852
5335
5456
5495